« ความเห็นที่ #6 เมื่อ: 01/05/18 เวลา 21:40:48 » |
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Stimulants and Anhedonia Stimulants like cocaine and methamphetamine have direct action on dopamine and its receptors in the brain, reducing the uptake of the neurotransmitter, which is the source of the extreme euphoria these drugs can cause. However, another result of this action is that, over time, the dopamine receptor cells in the brain can be damaged or even die off, as described in a study from the European Journal of Pharmacology. The result of this brain damage is a condition called anhedonia, which is a diminished ability, or even lack of ability, to feel pleasure if the drug is not being used. Because this is the result of actual cell death, the lack of ability to feel pleasure can last long after use of the drug is stopped. The follow-up result then can be deep depression, including suicidal thoughts and self-destructive actions. However, with treatment and continued abstinence from the substance, dopamine receptors and capabilities can repair and return to some function. ดูจากทรงแล้วก็น่าจะสัมพันธ์กับdepression อยู่นะครับ
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